Dissociation of Regional Activity in Default Mode Network in Medication-Naive, First-Episode Somatization Disorder

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Dissociation of Regional Activity in Default Mode Network in Medication-Naive, First-Episode Somatization Disorder

BACKGROUND Patients with somatization disorder (SD) have altered neural activity in the brain regions of the default mode network (DMN). However, the regional alteration of the DMN in SD remains unknown. The present study was designed to investigate the regional alterations of the DMN in patients with SD at rest. METHODS Twenty-five first-episode, medication-naive patients with SD and 28 age-...

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Rumination and Default Mode Network Subsystems Connectivity in First-episode, Drug-Naive Young Patients with Major Depressive Disorder

Neuroimaging evidence implicates the association between rumination and default mode network (DMN) in major depressive disorder (MDD). However, the relationship between rumination and DMN subsystems remains incompletely understood, especially in patients with MDD. Thirty-three first-episode drug-naive patients with MDD and thirty-three healthy controls (HCs) were enrolled and underwent resting-...

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Clinical significance of increased cerebellar default-mode network connectivity in resting-state patients with drug-naive somatization disorder

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2014

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0099273